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The term "personnel manual" is often used interchangeably with "employee handbook." Both terms refer to a comprehensive document that outlines the policies, procedures, and expectations for employees within an organization. A personnel manual typically includes information on topics such as employment policies, workplace behavior, benefits, and the rights and responsibilities of employees, similar to an employee handbook. This terminology is well-established in human resources and organizational contexts, making it a familiar point of reference for both managers and employees.

In contrast, the other terms do not carry the same meaning. "Management guidelines" refers more to directives intended for managers rather than a broader audience of employees. "Employee brief" suggests a concise overview rather than a detailed document, while "company policy document" could represent a variety of policies without the employee-focused structure that an employee handbook or personnel manual provides. Thus, personnel manual is the most accurate synonym for employee handbook in common usage.